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ASIC1 Antibody (RPE)

Mouse monoclonal to ASIC1 (RPE) . Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4. 3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety..

Product Specifications

Product Name Alternative

ASIC1, ACCN2, BNAC2, Acid-sensing ion channel 1, Acid-sensing (proton-gated) ion channel, Amiloride-sensitive cation channel 2 neuronal, Brain sodium channel 2

UniProt

Q6NXK8

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1

Target

ASIC1

Clonality

Monoclonal

Clone

N271/44 (Formerly sold as S271-44)

Conjugation

RPE

Field of Research

Neuroscience; Metabolism Research

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000)

Molecular Weight

60kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of ASIC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, IHC, WB

NCBI Accession Number

NP_033727.1

Host or Source

Mouse

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Isotype

IgG1

Entrez

11419

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