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Stargazin Antibody (Biotin)

Mouse monoclonal to TARP Gamma2 (Biotin) . Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T) . Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival..

Product Specifications

Product Name Alternative

CACNG2, Calcium channel voltage dependent gamma subunit 2, CaV gamma 2, Ipr328, MGC123981, MGC138502, MGC138504, Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin, Stg, Stargazer, TARP, TARP gamma-2, Transmembrane AMPAR regulatory protein gamma-2, AW060990, B230105C07Rik, B930041E13Rik, Wag, Waggler

UniProt

Q71RJ2

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2

Target

Stargazin

Clonality

Monoclonal

Clone

N245/36 (Formerly sold as S245-36)

Conjugation

Biotin

Field of Research

Neuroscience

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100)

Molecular Weight

35-55kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of TARP Gamma2/4/8 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, WB

NCBI Accession Number

NP_445803.1

Host or Source

Mouse

Preservative

136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate

Isotype

IgG2A

Entrez

84347

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