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LRP4 Antibody (RPE)

Mouse monoclonal to LRP4 (RPE) . Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway..

Product Specifications

Product Name Alternative

LRP4, LRP-4, LRP10, MEGF7, Low density lipoprotein receptor related protein 4, Multiple epidermal growth factor like domains 7, LDLR dan, LDLR, KIAA0816, Corin

UniProt

Q8VI56

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

Target

LRP4

Clonality

Monoclonal

Clone

N207/27 (Formerly sold as S207-27)

Conjugation

RPE

Field of Research

Metabolism Research

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100)

Molecular Weight

215kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of LRP4 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, WB

NCBI Accession Number

NP_766256.3

Host or Source

Mouse

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Isotype

IgG2A

Entrez

83469

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