Dicer Antibody (PerCP)

Mouse monoclonal to Dicer (PerCP) . Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) . After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha, pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs. The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA..

Product Specifications

Product Name Alternative

Dicer1, DCR, DCR1, DCR-1, Double-strand-specific ribonuclease, Helicase with RNase motif, HERNA, Helicase MOI, KIAA0928, Endoribonuclease Dicer

UniProt

Q8R418

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer

Target

Dicer

Clonality

Monoclonal

Clone

N167/7 (Formerly sold as S167-7)

Conjugation

PerCP

Field of Research

Cancer Biology

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100)

Molecular Weight

215kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.