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MGluR5 Antibody (RPE)

Mouse monoclonal to mGluR1 (RPE) . The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers..

Product Specifications

Product Name Alternative

MGluR5, mGlu5, GRM5, GPRC1E, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, Glutamate receptor metabotropic 5, mGluR5a, mGluR5b, mGluR, Glutamate receptor metabotropic 1, mGlu1, mGluR1, GRM1, GRM 1, GRM1A, GRM1 alpha, GRM1_HUMAN, GPRC1A, Metabotropic glutamate receptor 1, mGluR1 alpha

UniProt

P31424

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b

Target

MGluR5

Clonality

Monoclonal

Clone

N75/33 (Formerly sold as S75-33)

Conjugation

RPE

Field of Research

Metabolism Research

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100)

Molecular Weight

130kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of mGluR1/5 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, IHC, IP, WB

NCBI Accession Number

NP_058708.1

Host or Source

Mouse

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Isotype

IgG1

Entrez

24418

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