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Ankyrin G Antibody (Biotin)

Mouse monoclonal to Ankyrin G (Biotin) . Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton. Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane..

Product Specifications

Product Name Alternative

Ankyrin G, Ankyrin-G, Ankyrin-3, Ankyrin 3, ANK3, ANK-3, Ankyrin 3 (G), Ankyrin G119, Ankryin G119, Brain-specific ankyrin G, CHANK3, Node of Ranvier (ankyrin G), Node of Ranvier, FLJ45464, OTTHUMP00000217458, OTTHUMP00000217575, RP11-369L1.1

UniProt

Q12955

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein 1000 C-terminal amino acids of human Ankyrin G (also known as ANK-3 or ankyrin-3) encompassing all of Ankyrin G with the exception of Ankyrin repeats

Target

Ankyrin G

Clonality

Monoclonal

Clone

N106/20 (Formerly sold as S106-20)

Conjugation

Biotin

Field of Research

Cell Biology, Disease Biomarkers, Neuroscience, Protein Biochemistry, Signal Transduction

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100)

Molecular Weight

200kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Ankyrin-G in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, WB

NCBI Accession Number

NP_066267.2

Host or Source

Mouse

Preservative

136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate

Isotype

IgG1

Entrez

288

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