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TRPC5 Antibody (RPE)

Mouse monoclonal to TrpC5 (RPE) . Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homo-multimeric TRPC5 and hetero-multimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin. This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as chloroform, halothane and propofol..

Product Specifications

Product Name Alternative

Htrp5, Short transient receptor potential channel 5, TRP5

UniProt

Q9UL62

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)

Target

TRPC5

Clonality

Monoclonal

Clone

N67/15 (Formerly sold as S67-15)

Conjugation

RPE

Field of Research

Metabolism Research

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100)

Molecular Weight

110kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of TrpC5 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

AM, IHC, IP, WB

NCBI Accession Number

NP_036603.1

Host or Source

Mouse

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Isotype

IgG2b

Entrez

7224

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