TRPC7 Antibody (APC)

Mouse monoclonal to TrpC7 (APC) . Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway. TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure..

Product Specifications

Product Name Alternative

TRP7, KNP3, TRPM2, transient receptor potential cation channel subfamily C member 7

UniProt

Q9HCX4

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide amino acids 845-862 of human TRPC7

Target

TRPC7

Clonality

Monoclonal

Clone

N64A/36 (Formerly sold as S64A-36)

Conjugation

APC

Field of Research

Neuroscience

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100)

Molecular Weight

100kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of TrpC7 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.