Nav1.8 Antibody (FITC)
Mouse monoclonal to Nav1 (FITC) . 8. Nav1. 8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1. 8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1. 8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals..
Product Specifications
Product Name Alternative
UniProt
Q62968
Reactivity
Human, Monkey, Mouse, Rat
Immunogen
Fusion protein amino acids 1724-1956 of rat Nav1.8
Target
Nav1.8
Clonality
Recombinant
Clone
S134
Conjugation
FITC
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:1000), ICC/IF (1:100)
Molecular Weight
220kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
Tested Applications
AM, ICC, IF, IHC, WB
NCBI Accession Number
NP_058943.1
Host or Source
Mouse
Preservative
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Isotype
IgG2a
Entrez
29571
Frequently Asked Questions
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