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HCAII-IN-9

HCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability[1].

Product Specifications

CAS Number

2878477-18-8

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hcaii-in-9.html

Solubility

10 mM in DMSO

Smiles

CC1=CC(C)=CC(C(NC2=CC(Cl)=C(C=C2S(N)(=O)=O)S(N)(=O)=O)=O)=C1

Molecular Formula

C15H16ClN3O5S2

Molecular Weight

417.89

References & Citations

[1]Hussain Z, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7 (50) :47251-47264.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA II; CA IX; CA XII

Available Sizes

Frequently Asked Questions

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