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SHANK1 Antibody (APC)

Mouse monoclonal to SHANK1 (APC) . Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo..

Product Specifications

Product Name Alternative

GKAP/SAPAP interacting protein, OTTHUMP00000174437, SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, SH3/ankyrin domain gene 1, SHAN1_HUMAN, SHANK 1, Shank1, Shank1a, Somatostatin receptor interacting protein, Somatostatin receptor-interacting protein, SPANK 1, SPANK1, SSTR interacting protein, SSTR-interacting protein, SSTRIP, Synamon

UniProt

Q9WV48

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1

Target

SHANK1

Clonality

Monoclonal

Clone

N22/21 (Formerly sold as S22-21)

Conjugation

APC

Field of Research

Neuroscience

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:1000), ICC/IF (1:100)

Molecular Weight

190-220 kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Shank1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

AM, IHC, WB

NCBI Accession Number

NP_113939.2

Host or Source

Mouse

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Isotype

IgG1

Entrez

78957

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