E (c (RGDfK) ) 2
E (c (RGDfK) ) is an αvβ3 integrin-specific binding moiety with tumor targeting properties. Increased uptake of E (c (RGDfK) ) in human ovarian cancer OVCAR-3 xenograft tumors may be useful in cancer research[1].
Product Specifications
CAS Number
250612-47-6
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-c-rgdfk.html
Purity
99.82
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC([C@@H](N)CCC(NCCCC[C@@H]2NC([C@H](NC([C@@H](NC(CNC([C@@H](NC2=O)CCCNC(N)=N)=O)=O)CC(O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)[C@H]1CC4=CC=CC=C4
Molecular Formula
C59H87N19O16
Molecular Weight
1318.44
References & Citations
[1]Polyak D, et al. Development of PEGylated doxorubicin‐E‐[c (RGDfK) 2] conjugate for integrin‐targeted cancer therapy[J]. Polymers for Advanced Technologies, 2011, 22 (1) : 103-113.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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