DUX4 Antibody (FITC)
Mouse monoclonal to DUX4 (FITC) . DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4) . In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues..
Product Specifications
Product Name Alternative
Double homeobox 4, Double homeobox 10, DUX10, Double homeobox protein 4/10, DUX4L, DUX4L1
UniProt
F5GZ66
Reactivity
Human, Mouse
Immunogen
C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
Target
DUX4
Clonality
Monoclonal
Clone
P2B1
Conjugation
FITC
Field of Research
Stem Cell & Developmental Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:1000)
Molecular Weight
45kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_149418.3
Host or Source
Mouse
Preservative
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Isotype
IgG1
Entrez
22947
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