DUX4 Antibody (APC)
Mouse monoclonal to DUX4 (APC) . DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4) . In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues..
Product Specifications
Product Name Alternative
Double homeobox 4, Double homeobox 10, DUX10, Double homeobox protein 4/10, DUX4L, DUX4L1
UniProt
F5GZ66
Reactivity
Human, Mouse
Immunogen
C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
Target
DUX4
Clonality
Monoclonal
Clone
P2B1
Conjugation
APC
Field of Research
Stem Cell & Developmental Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:1000)
Molecular Weight
45kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_149418.3
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG1
Entrez
22947
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human Golgin subfamily A member 8K (GOG8K)
Recombinant Human Golgin subfamily A member 8K (GOG8K)