Pertussis Toxin Substrate HCAM-2

<strong>Pertussis Toxin Substrate HCAM-2 </strong>_x000D_ <strong>Catalog number:</strong> B2011233_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 2613.1 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> HCAM-2, pertussis toxin substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Burns DL. Secretion of Pertussis Toxin from Bordetella pertussis Toxins (Basel). 2021 Aug 18;13(8):574._x000D_ 2: Iiri T, Ohoka Y, Ui M, Katada T. Modification of the function of pertussis toxin substrate GTP-binding protein by cholera toxin-catalyzed ADP-ribosylation J Biol Chem. 1992 Jan 15;267(2):1020-6._x000D_ 3: Stanley JB, Gorczynski RM, Delovitch TL, Mills GB. IL-2 secretion is pertussis toxin sensitive in a T lymphocyte hybridoma J Immunol. 1989 May 15;142(10):3546-52._x000D_ 4: Iiri T, Ohoka Y, Ui M, Katada T. Functional modification by cholera-toxin-catalyzed ADP-ribosylation of a guanine-nucleotide-binding regulatory protein serving as the substrate of pertussis toxin Eur J Biochem. 1991 Dec 5;202(2):635-41._x000D_ 5: Backlund PS Jr, Aksamit RR, Unson CG, Goldsmith P, Spiegel AM, Milligan G. Immunochemical and electrophoretic characterization of the major pertussis toxin substrate of the RAW264 macrophage cell line Biochemistry. 1988 Mar 22;27(6):2040-6._x000D_ 6: Gilmore W, Weiner LP. The effects of pertussis toxin and cholera toxin on mitogen-induced interleukin-2 production: evidence for G protein involvement in signal transduction Cell Immunol. 1988 May;113(2):235-50._x000D_ 7: Milligan G, Carr C, Gould GW, Mullaney I, Lavan BE. Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G-proteins following transfection of the human alpha 2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor with two pertussis toxin-sensitive G-proteins, Gi2 and Gi3 J Biol Chem. 1991 Apr 5;266(10):6447-55._x000D_ 8: Codina J, Hildebrandt J, Iyengar R, Birnbaumer L, Sekura RD, Manclark CR. Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium Proc Natl Acad Sci U S A. 1983 Jul;80(14):4276-80._x000D_ 9: Katada T. The inhibitory G protein G(i) identified as pertussis toxin-catalyzed ADP-ribosylation Biol Pharm Bull. 2012;35(12):2103-11._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/3711124">10: Gierschik P, Falloon J, Milligan G, Pines M, Gallin JI, Spiegel A. Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils J Biol Chem. 1986 Jun 15;261(17):8058-62.</a>_x000D_ _x000D_ <strong>Products Related to Pertussis Toxin Substrate HCAM-2 can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>