MSC-5046
MSC-5046 is a selective TEAD1 inhibitor[1].
Product Specifications
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/msc-5046.html
Smiles
FC(C=N1)=CN2C1=NC=C2C(NCC3=C(CNC(C=C)=O)C(F)=C(OC4=CC=C(F)C=C4)C=C3)=O
Molecular Formula
C24H18F3N5O3
Molecular Weight
481.43
References & Citations
[1]Carswell E, et al. Discovery of reversible and covalent TEAD 1 selective inhibitors MSC-1254 and MSC-5046 based on one scaffold[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129981.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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