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MSC-5046

MSC-5046 is a selective TEAD1 inhibitor[1].

Product Specifications

UNSPSC

12352005

Target

YAP

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/msc-5046.html

Smiles

FC(C=N1)=CN2C1=NC=C2C(NCC3=C(CNC(C=C)=O)C(F)=C(OC4=CC=C(F)C=C4)C=C3)=O

Molecular Formula

C24H18F3N5O3

Molecular Weight

481.43

References & Citations

[1]Carswell E, et al. Discovery of reversible and covalent TEAD 1 selective inhibitors MSC-1254 and MSC-5046 based on one scaffold[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129981.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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