CAY10657
CAY10657 is an inhibitor for NF-κB pathway. CAY10657 downregulates expressions of proinflammatory cytokine (IL-6) and chemokine (MCP-1), and thus exhibits anti-inflammatory efficacy against meningitis induced by Streptococcus suis[1].
Product Specifications
CAS Number
494772-86-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cay10657.html
Smiles
O=C(C(SC(C1=CC=C(CN2CCOCC2)C=C1)=C3)=C3NC(N)=O)N
Molecular Formula
C17H20N4O3S
Molecular Weight
360.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Yang XP, et al., EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis. J Neuroinflammation. 2016 Oct 19;13 (1) :274.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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