Abametapir
Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2].
Product Specifications
CAS Number
1762-34-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MMP; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/abametapir.html
Purity
99.89
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC1=CN=C(C2=NC=C(C)C=C2)C=C1
Molecular Formula
C12H12N2
Molecular Weight
184.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Vernon Morrison Bowles, et al. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Glob Pediatr Health. 2019; 6: 2333794X19831295.|[2]Vernon M. Bowles, et al. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae) . J Med Entomol. 2017 Jan; 54 (1) : 167-172.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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