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Abametapir

Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2].

Product Specifications

CAS Number

1762-34-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MMP; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/abametapir.html

Purity

99.89

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC1=CN=C(C2=NC=C(C)C=C2)C=C1

Molecular Formula

C12H12N2

Molecular Weight

184.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Vernon Morrison Bowles, et al. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Glob Pediatr Health. 2019; 6: 2333794X19831295.|[2]Vernon M. Bowles, et al. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae) . J Med Entomol. 2017 Jan; 54 (1) : 167-172.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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