Demethoxycapillarisin
Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].
Product Specifications
CAS Number
[61854-36-2]
Product Name Alternative
6-Demethoxycapillarisin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PEPCK
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/demethoxycapillarisin.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C1C=C(OC2=CC=C(O)C=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C15H10O6
Molecular Weight
286.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Govorko D, et al. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab. 2007 Dec;293 (6) :E1503-10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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