CTnT/TNNT2 (Native Human)

<strong>cTnT/TNNT2 (Native Human)</strong>_x000D_ <strong>Catalog number:</strong> B2016824_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> Native Human cTnT/TNNT2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Sequeira V, Wang L, Wijnker PJM, Kim K, Pinto JR, Dos Remedios C, Redwood C, Knollmann BC, van der Velden J. Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy J Mol Cell Cardiol Plus. 2022 Sep;1:100007._x000D_ 2: du Fay de Lavallaz J, Prepoudis A, Wendebourg MJ, Kesenheimer E, Kyburz D, Daikeler T, Haaf P, Wanschitz J, L√∂scher WN, Schreiner B, Katan M, Jung HH, Maurer B, Hammerer-Lercher A, Mayr A, Gualandro DM, Acket A, Puelacher C, Boeddinghaus J, Nestelberger T, Lopez-Ayala P, Glarner N, Shrestha S, Manka R, Gawinecka J, Piscuoglio S, Gallon J, Wiedemann S, Sinnreich M, Mueller C; BASEL XII Investigators. Skeletal Muscle Disorders: A Noncardiac Source of Cardiac Troponin T Circulation. 2022 Jun 14;145(24):1764-1779._x000D_ 3: Li B, Zhan Y, Liang Q, Xu C, Zhou X, Cai H, Zheng Y, Guo Y, Wang L, Qiu W, Cui B, Lu C, Qian R, Zhou P, Chen H, Liu Y, Chen S, Li X, Sun N. Isogenic human pluripotent stem cell disease models reveal ABRA deficiency underlies cTnT mutation-induced familial dilated cardiomyopathy Protein Cell. 2022 Jan;13(1):65-71._x000D_ 4: Langa P, Shafaattalab S, Goldspink PH, Wolska BM, Fernandes AA, Tibbits GF, Solaro RJ. A perspective on Notch signalling in progression and arrhythmogenesis in familial hypertrophic and dilated cardiomyopathies Philos Trans R Soc Lond B Biol Sci. 2023 Jun 19;378(1879):20220176._x000D_ 5: Cai H, Li B, Bai A, Huang J, Zhan Y, Sun N, Liang Q, Xu C. Establishing a new human hypertrophic cardiomyopathy-specific model using human embryonic stem cells Exp Cell Res. 2020 Feb 1;387(1):111736._x000D_ 6: Florido R, Lee AK, McEvoy JW, Hoogeveen RC, Koton S, Vitolins MZ, Shenoy C, Russell SD, Blumenthal RS, Ndumele CE, Ballantyne CM, Joshu CE, Platz EA, Selvin E. Cancer Survivorship and Subclinical Myocardial Damage Am J Epidemiol. 2019 Dec 31;188(12):2188-2195._x000D_ 7: Starnberg K, Frid√©n V, Muslimovic A, Ricksten SE, Nystr√∂m S, Forsgard N, Lindahl B, Vukusic K, Sandstedt J, Dellgren G, Hammarsten O. A Possible Mechanism behind Faster Clearance and Higher Peak Concentrations of Cardiac Troponin I Compared with Troponin T in Acute Myocardial Infarction Clin Chem. 2020 Feb 1;66(2):333-341._x000D_ 8: Gamaza-Chuli√°n S, Le√≥n-Jim√©nez J, Recuerda-N√∫√±ez M, Camacho-Freire S, Guti√©rrez-Barrios A, Vargas-Machuca JC. Cardiac troponin-T in acute pericarditis J Cardiovasc Med (Hagerstown). 2014 Jan;15(1):68-72._x000D_ 9: Luedde M, Ehlermann P, Weichenhan D, Will R, Zeller R, Rupp S, M√ºller A, Steen H, Ivandic BT, Ulmer HE, Kern M, Katus HA, Frey N. Severe familial left ventricular non-compaction cardiomyopathy due to a novel troponin T (TNNT2) mutation Cardiovasc Res. 2010 Jun 1;86(3):452-60._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27930352">10: Singh VP, Mathison M, Patel V, Sanagasetti D, Gibson BW, Yang J, Rosengart TK. MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1 J Am Heart Assoc. 2016 Nov 10;5(11):e003922. </a>_x000D_ _x000D_ <strong>Products Related to cTnT/TNNT2 (Native Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>