Autophagy-lysosome activator-1

Autophagy-lysosome activator-1 (Compound F1) is a Autophagy-lysosome activator. Autophagy-lysosome activator-1 effectively induces PD-L1 or VISTA degradation in tumor cells[1].

Product Specifications

UNSPSC

12352005

Target

Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/autophagy-lysosome-activator-1.html

Smiles

OCCNCC1=CC=CC(NC2=NN=C(C3=CC=CC=C3)O2)=C1

Molecular Formula

C17H18N4O2

Molecular Weight

310.35

References & Citations

[1]Wang K, et al. Discovery of small molecules for autophagy-lysosome degradation of immune checkpoint proteins. Eur J Med Chem. 2024 Oct 16;280:116958.