Rabbit CD3 epsilon&CD3 gamma Heterodimer Protein, His Tag&Flag Tag (MALS verified)
Rabbit CD3E&CD3G Heterodimer Protein, His Tag&Flag Tag (CDG-RB52D5) is expressed from human 293 cells (HEK293) . It contains AA Gln 22 - Thr 120 (CD3E) & Gln 23 - Asn 111 (CD3G) (Accession # Q9TUF9-1 (CD3E) & G1SDA3-1 (CD3G) ) .
Product Specifications
Background
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Specifications
Rabbit CD3E&CD3G Heterodimer Protein, His Tag&Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 16.5 kDa (CD3E) and 15.0 kDa (CD3G) . Subunit CD3E is fused with a polyhistidine tag at the C-terminus and subunit CD3G is fused with a flag tag at the C-terminus. The reducing (R) heterodimer protein migrates as 18-20 kDa and 23 kDa due to glycosylation.
Accession Number
Q9TUF9-1 (CD3E) & G1SDA3-1 (CD3G)
Expression Region
Gln 22 - Thr 120 (CD3E) & Gln 23 - Asn 111 (CD3G)
Host
HEK293
Target
CD3E & CD3G
Conjugation
Unconjugated
Tag
C-10xHis | C-Flag
Source
Rabbit
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
16.5 kDa & 15.0 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
250ug*4
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CDG-RB52D5.pdf
Species
Rabbit
Curated Selection
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