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Caprospinol

Product Specifications

UNSPSC Description

Caprospinol (SP-233) is a steroid compound candidate based on the structure of 22R-hydroxycholesterol. It has multiple mechanisms of neuroprotection, including binding to β-amyloid protein (Aβ(42)), interacting with the mitochondrial respiratory chain, clearing Aβ(42) monomers, and acting as a σ-1 receptor ligand. It can cross the blood-brain barrier in vivo and restore cognitive impairment, and has the potential to inhibit Alzheimer's disease.

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/caprospinol.html

Smiles

C[C@@]12[C@]3([H])[C@@](C[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)OC(CCCCC)=O)=CC4)C)([H])CC2)([H])O[C@]6(CC[C@H](CO6)C)[C@H]3C

Molecular Weight

512.76

References & Citations

[1]Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties|[2]Caprospinol: moving from a neuroactive steroid to a neurotropic drug

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-119196/Caprospinol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-119196/

Clinical Information

No Development Reported

CAS Number

4952-56-1

Curated Selection

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