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IMP2-IN-2

Product Specifications

UNSPSC Description

IMP2-IN-2 (compound 6) is a potent and selective IMP2 inhibitor, with IC50s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer[1].

Target Antigen

Insulin Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/imp2-in-2.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(NC(N(CC)CC2=CC=CC=C2)=O)C=C(C3=CC=C(C(F)(F)F)C=C3)S1)O

Molecular Weight

448.46

References & Citations

[1]Dahlem C, et, al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022 Feb 18;17(2):361-375.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-146179/IMP2-IN-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-146179/IMP2-IN-2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1448353-39-6

Available Sizes

Curated Selection

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