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IMP2-IN-2

IMP2-IN-2 (compound 6) is a potent and selective IMP2 inhibitor, with IC50s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer[1].

Product Specifications

CAS Number

1448353-39-6

UNSPSC

12352005

Target

Insulin Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/imp2-in-2.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(NC(N(CC)CC2=CC=CC=C2)=O)C=C(C3=CC=C(C(F)(F)F)C=C3)S1)O

Molecular Formula

C22H19F3N2O3S

Molecular Weight

448.46

References & Citations

[1]Dahlem C, et, al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022 Feb 18;17 (2) :361-375.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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