Benzamidine (hydrochloride)
Benzamidine hydrochloride is a trypsin-like serine proteases with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1].
Product Specifications
CAS Number
1670-14-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/benzamidine-hydrochloride.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
[H]Cl.N=C(C1=CC=CC=C1)N
Molecular Formula
C7H9ClN2
Molecular Weight
156.62
Precautions
H302, H315, H319, H335
References & Citations
[1]Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7 (4) :299-312.|[2]J A Cairns, et al. Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J Clin Invest. 1997 Mar 15;99 (6) :1313-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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