Mauritianin

Mauritianin is an orally active kaempferol glycoside. Mauritianin can be isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Mauritianin has hepatoprotective, neuroprotective, and renoprotective activities. Mauritianin increases vascular tone when used in combination with Alcesefoliside (HY-N5049) [1][2][3][4].

Product Specifications

CAS Number

[109008-28-8]

UNSPSC

12352005

Target

Topoisomerase

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/mauritianin.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(O[C@H]2[C@@H]([C@H]([C@@H](O)[C@@H](CO[C@H]3[C@@H]([C@@H]([C@@H](O)[C@H](C)O3)O)O)O2)O)O[C@@]4([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O4)O)O)=C(C5=CC=C(O)C=C5)OC6=CC(O)=CC(O)=C61

Molecular Formula

C33H40O19

Molecular Weight

740.66

References & Citations

[1]Nahrstedt A, et al. Flavonoids from Acalypha indica. Fitoterapia. 2006 Sep;77 (6) :484-6.|[2]Ma J, et al. DNA topoisomerase I inhibitors from Rinorea anguifera. Bioorg Med Chem Lett. 2005 Feb 1;15 (3) :813-6.|[3]Kadinov B G, et al. In vitro effects of alcesefoliside and mauritianin, isolated from Astragalus monspessulanus subsp. monspessulanus, on the contractility of a. basilaris. Pharmacia, 2023, 70: 15-19. |[4]Manov V, et al. In vivo protective effects of Mauritianin. 2023.