GSK-3 inhibitor 6
GSK-3 inhibitor 6 (2) is a CNS penetrated GSK-3 inhibitor, with IC50 values of 29 nM and 24 nM for GSK-3α and GSK-3β, respectively[1].
Product Specifications
CAS Number
1772823-37-6
UNSPSC
12352101
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gsk-3-inhibitor-6.html
Smiles
O=C(NC1=C(C2=CC=C(F)C=C2)C=CN=C1)C3=CC=NC(NC(C4CC4)=O)=C3
Molecular Formula
C21H17FN4O2
Molecular Weight
376.38
References & Citations
[1]Surendra Reddy Gundam, et al. Synthesis and preliminary evaluation of novel PET probes for GSK-3 imaging. Sci Rep. 2024 Jul 10;14 (1) :15960.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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