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N-(Azido-PEG2)-N-Boc-PEG3-NHS ester

Product Specifications

UNSPSC Description

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-azido-peg2-n-boc-peg3-nhs-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)N(CCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

Molecular Weight

575.61

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140559/N-Azido-PEG2-N-Boc-PEG3-NHS-ester-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140559/

Clinical Information

No Development Reported

CAS Number

2093153-85-4

Available Sizes

Curated Selection

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