Rac1/CDC42 (Phospho Ser71) rabbit pAb
Product Specifications
Product Name Alternative
Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1)
UniProt
P63000/P15153/P60763/P60953
Swiss Prot
P63000/P15153/P60763/P60953
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)
Target
Rac1/CDC42
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity) . In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity) . Activation by GTP-binding promotes nuclear localization (PubMed:12551911) . .
Other Product Names
Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1)
Gene ID (Human)
5879
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