S6K Substrate (Highly Pure)

<strong>S6K Substrate (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2012870_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> S6K_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Takeda E, Matsuura A. A substrate localization model for the selective regulation of TORC1 downstream pathways Commun Integr Biol. 2018 Jun 18;11(2):1-4._x000D_ 2: Artemenko M, Zhong SSW, To SKY, Wong AST. p70 S6 kinase as a therapeutic target in cancers: More than just an mTOR effector Cancer Lett. 2022 Jun 1;535:215593._x000D_ 3: Moustafa-Kamal M, Kucharski TJ, El-Assaad W, Abbas YM, Gandin V, Nagar B, Pelletier J, Topisirovic I, Teodoro JG. The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest Cell Rep. 2020 Oct 6;33(1):108230._x000D_ 4: Chiku T, Hayashishita M, Saito T, Oka M, Shinno K, Ohtake Y, Shimizu S, Asada A, Hisanaga SI, Iijima KM, Ando K. S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy Neurobiol Aging. 2018 Nov;71:255-264._x000D_ 5: Destefano MA, Jacinto E. Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2) Biochem Soc Trans. 2013 Aug;41(4):896-901._x000D_ 6: Zhang Y, Zhang Y, Yu Y. Global Phosphoproteomic Analysis of Insulin/Akt/mTORC1/S6K Signaling in Rat Hepatocytes J Proteome Res. 2017 Aug 4;16(8):2825-2835._x000D_ 7: Ip CK, Wong AS. Exploiting p70 S6 kinase as a target for ovarian cancer Expert Opin Ther Targets. 2012 Jun;16(6):619-30._x000D_ 8: González-López O, Palacios-Nava BB, Peña-Uribe CA, Campos-García J, López-Bucio J, García-Pineda E, Reyes de la Cruz H. Growth promotion in Arabidopsis thaliana by bacterial cyclodipeptides involves the TOR/S6K pathway activation J Plant Physiol. 2021 Feb;257:153343._x000D_ 9: Li S, Guan S, Wang Y, Cheng L, Yang Q, Tian Z, Zhao M, Wang X, Feng B. Nicotine inhibits rapamycin-induced pain through activating mTORC1/S6K/IRS-1-related feedback inhibition loop Brain Res Bull. 2019 Jul;149:75-85._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30126834">10: Roy D, Kahler DJ, Yun C, Hubbard EJA. Functional Interactions Between rsks-1/S6K, glp-1/Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell Maintenance G3 (Bethesda). 2018 Oct 3;8(10):3293-3309. </a>_x000D_ _x000D_ <strong>Products Related to S6K Substrate (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>