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RS-25344

RS-25344 is a selective inhibitor of phosphodiesterase type IV (PDE4) . RS-25344 increases intracellular cAMP (cyclic adenosine phosphate) concentration by inhibiting PDE4 activity. RS-25344 can be used in the study of inflammation, immune diseases, neurodegenerative diseases and cardiovascular diseases[1].

Product Specifications

CAS Number

152814-89-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rs-25344.html

Smiles

O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O

Molecular Formula

C19H13N5O4

Molecular Weight

375.34

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Fisch J D, et al. Enhancement of motility and acrosome reaction in human spermatozoa: differential activation by type-specific phosphodiesterase inhibitors[J]. Human Reproduction (Oxford, England), 1998, 13 (5) : 1248-1254.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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