CSRM617 (Standard)
CSRM617 (Standard) is the analytical standard of CSRM617. This product is intended for research and analytical applications. CSRM617 is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 is well tolerated in the prostate cancer mouse model[1]
Product Specifications
CAS Number
787504-88-5
UNSPSC
12352005
Target
Androgen Receptor; Apoptosis; Reference Standards
Type
Reference compound
Related Pathways
Apoptosis; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csrm617-standard.html
Smiles
O=C(C(CO)N)N/N=C/C1=CC=C(C(O)=C1O)O
Molecular Formula
C10H13N3O5
Molecular Weight
255.23
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rat Matrix metallopeptidase 28, MMP28 ELISA KIT
Rat Matrix metallopeptidase 28, MMP28 ELISA KIT
