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TOOS

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound[1].

Product Specifications

CAS Number

[82692-93-1]

Product Name Alternative

TOOS sodium salt

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/TOOS.html

Purity

99.93

Solubility

DMSO : ≥ 47 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

O=S(CC(O)CN(CC)C1=CC=CC(C)=C1)(O[Na])=O

Molecular Formula

C12H18NNaO4S

Molecular Weight

295.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Lin X, et al. Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor. Talanta. 2021 Nov 1;234:122647.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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