Magnesium isoglycyrrhizinate (hydrate)

Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant (Glycyrrhiza glabra) . Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats[1].

Product Specifications

CAS Number

[658701-67-8]

UNSPSC

12352005

Target

Caspase; NOD-like Receptor (NLR)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/magnesium-isoglycyrrhizinate-hydrate.html

Purity

99.81

Solubility

H2O : 33.33 mg/mL (adjust pH to 9 with NH3·H2O)

Smiles

C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@]3([H])C[C@](C)(CC4)C(O)=O)C)C)=O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C([O-])=O)O)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C([O-])=O)C)([H])CC1)C.[Mg+2].O.O.O.O

Molecular Formula

C42H68MgO20

Molecular Weight

917.28

References & Citations

[1]Yang Y, et al., Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease. BMC Pulm Med. 2021 Nov 15;21 (1) :371.