Ginsenoside Rg2

Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS) . Ginsenoside Rg2 also reduces Aβ1-42 accumulation.

Product Specifications

CAS Number

[52286-74-5]

Product Name Alternative

Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Amyloid-β; NF-κB

Type

Natural Products

Related Pathways

Neuronal Signaling; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Neurological Disease; Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Ginsenoside-Rg2.html

Purity

98.11

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC6)C

Molecular Formula

C42H72O13

Molecular Weight

785.01

Precautions

H302, H315, H319, H335

References & Citations

[1]Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013 Apr;17 (2) :133-7.|[2]Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40 (1) :9-17.|[3]Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013;17 (2) :133-137.