Raludotatug

Raludotatug is a humanized anti-CDH6 IgG1 monoclonal antibody. Raludotatug has antitumor activity and can be used to synthesize the ADC molecule Raludotatug deruxtecan (HY-164734) [1].

Product Specifications

CAS Number

[2610074-56-9]

UNSPSC

12352203

Target

ADC Antibody; Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/raludotatug.html

Purity

99.00

Solubility

10 mM in DMSO

Smiles

[Raludotatug]

Molecular Weight

(145.702 kDa)

References & Citations

[1]Suzuki H, et al. Raludotatug Deruxtecan, a CDH6-Targeting Antibody-Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models. Mol Cancer Ther. 2024 Mar 4;23 (3) :257-271.