GNE-235
Product Specifications
UNSPSC Description
GNE-235 is a compound selective for the second bromodomain of PBRM1, with a KD of 0.28 ± 0.02 μM. GNE-235 can be used for evaluation of the cellular function of PBRM1[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gne-235.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H]1CCCN1C2=C(N)N=NC(C3=CC=CO3)=C2
Molecular Weight
244.29
References & Citations
[1]Cochran AG, et al. GNE-235: A Lead Compound Selective for the Second Bromodomain of PBRM1. J Med Chem. 2023 Sep 28;66(18):13116-13134.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150289/GNE-235-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150289/GNE-235-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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