N-desmethyl Enzalutamide
N-desmethyl Enzalutamide is the active metabolite of Enzalutamide.N-desmethyl Enzalutamide is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide[1].
Product Specifications
CAS Number
[1242137-16-1]
Product Name Alternative
N-desmethyl MDV 3100
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/N-desmethyl-Enzalutamide.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=C(N1C2=CC(F)=C(C(N)=O)C=C2)N(C3=CC=C(C(C(F)(F)F)=C3)C#N)C(C(C)1C)=O
Molecular Formula
C20H14F4N4O2S
Molecular Weight
450.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Gibbons JA, et al. Pharmacokinetic Drug Interaction Studies with Enzalutamide. Clin Pharmacokinet. 2015 Oct;54 (10) :1057-69.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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