1-Methylcytosine
1-Methylcytosine is a methylated form of the DNA base cytosine and used as a nucleobase of hachimoji DNA, in which it pairs with Isoguanine[1][2].
Product Specifications
CAS Number
1122-47-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-Methylcytosine.html
Concentration
10mM
Purity
99.01
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC(C=CN1C)=NC1=O
Molecular Formula
C5H7N3O
Molecular Weight
125.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Kistenmacher, T. J.; Rossi, M. (1977-12-15) . "1-Methylcytosine: a refinement". Acta Crystallographica (1977) Section B. 33 (12) : 3962–3965.|[2]Hoshika S, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 Feb 22;363 (6429) :884-887.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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