Nidulin

Nidulin (Methylustin) is a depsidone isolated from a marine fungus Aspergillus unguis. Nidulin shows antifungal and antibacterial against pathogenetic strains, Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus and Candida albicans with inhibition zones of 9.5 mm, 9.0 mm and 9.0 mm, respectively. Nidulin exhibits potent larvicidality against brine shrimp[1].

Product Specifications

CAS Number

[10089-10-8]

Product Name Alternative

Methylustin

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Bacterial; Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nidulin.html

Smiles

O=C1C2=C(C)C(Cl)=C(O)C(Cl)=C2OC3=C(/C(C)=C/C)C(Cl)=C(OC)C(C)=C3O1

Molecular Formula

C20H17Cl3O5

Molecular Weight

443.70

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Yang WC, et al. Depsidone Derivatives and a Cyclopeptide Produced by Marine Fungus Aspergillus unguis under Chemical Induction and by Its Plasma Induced Mutant. Molecules. 2018 Sep 3;23 (9) :2245.