PARP7-IN-21
PARP7-IN-21 (compound 128) is a potent inhibitor of PARP7, with the IC50 of [1].
Product Specifications
CAS Number
3034666-02-6
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp7-in-21.html
Smiles
O=C1NN=C2C(CC[C@H]2N3C[C@](C(N4CCN(C5=CC=C(C#N)C=N5)CC4)=O)(C)CC3)=C1C(F)(F)F
Molecular Formula
C24H26F3N7O2
Molecular Weight
501.50
References & Citations
[1]Azkarra Therapeutics, Inc.; Oregon Health, et al. Preparation of pyridazin-3 (2H) -one and pyridin-2 (1H) -one PARP inhibitor compounds. World Intellectual Property Organization, WO2024073133 A1 2024-04-04
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP7
Frequently Asked Questions
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