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PARP7-IN-21

PARP7-IN-21 (compound 128) is a potent inhibitor of PARP7, with the IC50 of [1].

Product Specifications

CAS Number

3034666-02-6

UNSPSC

12352005

Target

PARP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/parp7-in-21.html

Smiles

O=C1NN=C2C(CC[C@H]2N3C[C@](C(N4CCN(C5=CC=C(C#N)C=N5)CC4)=O)(C)CC3)=C1C(F)(F)F

Molecular Formula

C24H26F3N7O2

Molecular Weight

501.50

References & Citations

[1]Azkarra Therapeutics, Inc.; Oregon Health, et al. Preparation of pyridazin-3 (2H) -one and pyridin-2 (1H) -one PARP inhibitor compounds. World Intellectual Property Organization, WO2024073133 A1 2024-04-04

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PARP7

Frequently Asked Questions

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