Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NLRP3-IN-62

NLRP3-IN-62 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-62 inhibits pyroptosis in THP-1 cell with an IC50 of 0.7 nM, inhibits IL-β release with an IC50 of 108.5 nM[1].

Product Specifications

CAS Number

[3059965-71-5]

UNSPSC

12352005

Target

NOD-like Receptor (NLR) ; Pyroptosis

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nlrp3-in-62.html

Smiles

O=C1C=C2C(CN(C2)C3=NC4=NC(C5=C(C=C(C(F)(F)F)C=C5C)O)=CC=C4O3)=CN1

Molecular Formula

C21H15F3N4O3

Molecular Weight

428.36

References & Citations

[1]AITKEN LS, et al., Nlrp3 inhibitors. WO2024213552.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NLGN3 (Neuroligin-3, Gliotactin Homolog, KIAA1480, NL3, KIAA1480, ASPGX1, AUTSX1) (HRP)
MBS6387088-01 0.1 mL

NLGN3 (Neuroligin-3, Gliotactin Homolog, KIAA1480, NL3, KIAA1480, ASPGX1, AUTSX1) (HRP)

Ask
View Details
NLGN3 (Neuroligin-3, Gliotactin Homolog, KIAA1480, NL3, KIAA1480, ASPGX1, AUTSX1) (HRP)
MBS6387088-02 5x 0.1 mL

NLGN3 (Neuroligin-3, Gliotactin Homolog, KIAA1480, NL3, KIAA1480, ASPGX1, AUTSX1) (HRP)

Ask
View Details
EGFR/HER2-IN-11
HY-160613 1 Each

EGFR/HER2-IN-11

Ask
View Details
1-p-(Tolyloxy)-2,3-epoxypropane
TRC-T536678-2.5G 2.5 g

1-p-(Tolyloxy)-2,3-epoxypropane

Ask
View Details
CPT2 (carnitine palmitoyltransferase II, CPT1, CPTASE) (APC)
244899-APC 100 µL

CPT2 (carnitine palmitoyltransferase II, CPT1, CPTASE) (APC)

Ask
View Details
GNAT2 Rabbit Polyclonal Antibody
TA376643 100 µL

GNAT2 Rabbit Polyclonal Antibody

Ask
View Details