C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt)

C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) is a specific type of long-chain molecule found in murine skin[1]. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) promotes migration of both mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells at concentrations between 0.5-5 µM. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) ’s levels are higher in CFPAC-1 pancreatic ductal adenocarcinoma cells than in pancreatic cancer stem cells[2].

Product Specifications

CAS Number

[384835-48-7]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/c18-ceramide-1-phosphate-d18-1-18-0-ammonium-salt.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCC(N[C@@H](COP(O)(O)=O)[C@H](O)/C=C/CCCCCCCCCCCCC)=O.N

Molecular Formula

C36H75N2O6P

Molecular Weight

662.96

References & Citations

[1]Yamashita, R., et al. Analysis of molecular species profiles of ceramide-1-phosphate and sphingomyelin using MALDI-TOF mass spectrometry Lipids 51 (2),263-270 (2016) .|[2]Kuc, N., et al. Pancreatic ductal adenocarcinoma cell secreted extracellular vesicles containing ceramide-1-phosphate promote pancreatic cancer stem cell motility Biochem. Pharmacol. 156,458-466 (2018) .