Recombinant Mouse Solute carrier family 2, facilitated glucose transporter member 1 (Slc2a1), partial
Product Specifications
Product Name Alternative
Glucose transporter type 1, erythrocyte/brain
Abbreviation
Recombinant Mouse Slc2a1 protein, partial
Gene Name
Slc2a1
UniProt
P17809
Expression Region
451-492aa
Organism
Mus musculus (Mouse)
Target Sequence
KVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
Tag
Tag-Free
Type
Developed Protein
Source
E.coli
Field of Research
Signal Transduction
Relevance
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:17320047) . Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (By similarity) . Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (By similarity) .
Endotoxin
Not test
Purity
Greater than 85% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
4.5 kDa
References & Citations
"Implications of glucose transporter protein type 1 (GLUT1) -haplodeficiency in embryonic stem cells for their survival in response to hypoxic stress." Heilig C., Brosius F., Siu B., Concepcion L., Mortensen R., Heilig K., Zhu M., Weldon R., Wu G., Conner D. Am. J. Pathol. 163:1873-1885 (2003)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog