RP-182-PEG3-K(palmitic acid)
Product Specifications
UNSPSC Description
RP-182-PEG3-K palmitic acid (Compound 1a) inhibits CD206high M2-like macrophage (IC50 of 3.2 µM) and induces phagocytosis. RP-182-PEG3-K palmitic acid exhibits antitumor efficacy in mouse B16 melanoma allografts[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rp-182-peg3-k-palmitic-acid.html
Smiles
C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CCCCN)=O)CC1=CC=CC=C1)=O)CCCNC(N)=N)=O)CCCCN)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NCCOCCOCCOCC(N[C@@H](CCCCNC(CCCCCCCCCCCCCCC)=O)C(N)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CCCNC(N)=N)=O)=O)CC4=CC=CC=C4)=O
Molecular Weight
1929.48
References & Citations
[1]Singh SS, et al., Fatty acid derivatization and cyclization of the immunomodulatory peptide RP-182 targeting CD206high macrophages improves anti-tumor activity. Mol Cancer Ther. 2024 Aug 30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169089/RP-182-PEG3-K-palmitic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169089/
Clinical Information
No Development Reported
Curated Selection
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