PROTAC STAT3 degrader-3
PROTAC STAT3 degrader-3 (S3D1) is a STAT3 PROTAC degrader with anticancer activity (Structural notes: (Blue: Cereblon ligand , Black: linker; Pink: Pentafluorobenzenesulfonamide (Me) -CH2-CONH-benzamide (HY-163526) ).
Product Specifications
UNSPSC
12352005
Target
PROTACs; STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; PROTAC; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-stat3-degrader-3.html
Purity
99.7500
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(S(=O)(C1=C(C(F)=C(C(F)=C1F)F)F)=O)CC(NC2=CC=C(C=C2)C(NCCOCCNC3=C4C(N(C(C4=CC=C3)=O)C5CCC(NC5=O)=O)=O)=O)=O
Molecular Formula
C33H29F5N6O9S
Molecular Weight
780.68
References & Citations
[1]Wang Kefeng, et al. STAT3 inhibitor, PROTAC molecule, and preparation methods and applications thereof. U.S, CN117720443, 2024-03-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
